Plant Transcription factor database - Universität Potsdam
version: 3.0

Micromonas pusilla CCMP1545 SET Family


Marmorstein. 2003: The methylation of lysine residues on histone tails is catalyzed by proteins containing a conserved SET domain. A recent flurry of structures of SET domain proteins has revealed a new protein fold and a scaffold for understanding catalysis and substrate binding by these enzymes. The prospect that histone methylation might form an epigenetic code and the implicated involvement of SET domain proteins in cancer assures that structure-function studies of these enzymes will continue until their detailed mechanism of action is determined.

Members of this family
  SHOULD possess SET domain
  SHOULD NOT possess CXC PHD zf-C2H2 domains

Domain alignments

This family is also present in:


There are 18 gene models in this family

Gene modelDescriptionDomains
23211 e_gw1.16.393.1 SET
23446 e_gw1.17.155.1 SET
2803 gw1.3.306.1 SET
35752 estExt_Genewise1Plus.C_120013 SET
36635 estExt_Genewise1Plus.C_150278 Rubis-subs-bind SET
39853 fgenesh1_pg.C_scaffold_5000282 SET
40442 fgenesh1_pg.C_scaffold_7000036 SET
49889 EuGene.0000010113 SET
50024 EuGene.0000010248 SET
50136 EuGene.0000010360 SET
50859 EuGene.0000011083 SET
51358 EuGene.0000100429 SET
56583 EuGene.0000030737 SET
57043 EuGene.0000040169 ARID SET
57748 EuGene.0000050053 SET
60905 EuGene.0000090456 SET
62078 est_orfs.3_1061_4279892:1 SET YDG_SRA
7678 gw1.1.861.1 SET

General references

Marmorstein, R. 2003. Structure of SET domain proteins: a new twist on histone methylation. Trends Biochem. Sci. 28(2):59-62 PUBMEDID:12575990