Plant Transcription factor database - Universität Potsdam
version: 3.0

Ostreococcus tauri SET Family


Marmorstein. 2003: The methylation of lysine residues on histone tails is catalyzed by proteins containing a conserved SET domain. A recent flurry of structures of SET domain proteins has revealed a new protein fold and a scaffold for understanding catalysis and substrate binding by these enzymes. The prospect that histone methylation might form an epigenetic code and the implicated involvement of SET domain proteins in cancer assures that structure-function studies of these enzymes will continue until their detailed mechanism of action is determined.

Members of this family
  SHOULD possess SET domain
  SHOULD NOT possess CXC PHD zf-C2H2 domains

Domain alignments

This family is also present in:


There are 10 gene models in this family

Gene modelDescriptionDomains
16326 e_gw1.03.00.496.1 SET
19327 e_gw1. SET
21349 e_gw1. Rubis-subs-bind SET
22195 e_gw1. SET
24243 estExt_fgenesh1_pg.C_Chr_11.00010101 SET zf-CW
31924 0300010478 Rubis-subs-bind SET
32025 0300010579 SET
37391 1700010067 SET
4775 gw1. SET
6642 gw1. SET

General references

Marmorstein, R. 2003. Structure of SET domain proteins: a new twist on histone methylation. Trends Biochem. Sci. 28(2):59-62 PUBMEDID:12575990