Plant Transcription factor database - Universität Potsdam
version: 3.0

Selaginella moellendorffii SET Family


Marmorstein. 2003: The methylation of lysine residues on histone tails is catalyzed by proteins containing a conserved SET domain. A recent flurry of structures of SET domain proteins has revealed a new protein fold and a scaffold for understanding catalysis and substrate binding by these enzymes. The prospect that histone methylation might form an epigenetic code and the implicated involvement of SET domain proteins in cancer assures that structure-function studies of these enzymes will continue until their detailed mechanism of action is determined.

Members of this family
  SHOULD possess SET domain
  SHOULD NOT possess CXC PHD zf-C2H2 domains

Domain alignments

This family is also present in:


There are 36 gene models in this family

Gene modelDescriptionDomains
102436 e_gw1.26.558.1 SET
104841 e_gw1.30.307.1 Pre-SET SET YDG_SRA
107696 e_gw1.35.474.1 SET
110000 e_gw1.39.380.1 Rubis-subs-bind SET
110353 e_gw1.40.493.1 SET
111860 e_gw1.43.192.1 SET
123930 e_gw1.73.345.1 SET
139232 estExt_Genewise1.C_00100 Rubis-subs-bind SET
145424 estExt_Genewise1.C_100334 SET
166928 estExt_Genewise1Plus.C_41376 SET
3415 gw1.47.27.1 SET
402746 fgenesh2_pg.C_scaffold_0000751 SET
402971 fgenesh2_pg.C_scaffold_0000976 SET
406852 fgenesh2_pg.C_scaffold_6000103 Rubis-subs-bind SET
408995 fgenesh2_pg.C_scaffold_9000368 SET
414219 fgenesh2_pg.C_scaffold_23000083 SET
429412 fgenesh2_pg.C_scaffold_114000046 SET
430576 fgenesh2_pg.C_scaffold_134000008 SET
432361 fgenesh2_pg.C_scaffold_272000001 LRR_2 SET
432653 fgenesh2_pg.C_scaffold_628000001 SET
437298 estExt_fgenesh2_pg.C_00216 SET
445108 estExt_fgenesh2_pg.C_520130 FYRC FYRN PWWP SET
445692 estExt_fgenesh2_pg.C_600017 SET
446978 estExt_fgenesh2_pg.C_810070 SET
447801 estExt_fgenesh2_pg.C_1000071 SET
447947 estExt_fgenesh2_pg.C_1050053 LRR_2 SET
52721 gw1.38.369.1 SET
58820 gw1.18.733.1 SET
58821 gw1.18.734.1 SET
6548 gw1.5.105.1 SET
78627 e_gw1.2.1574.1 SET
79965 e_gw1.3.1059.1 Pre-SET SET YDG_SRA
80789 e_gw1.3.1160.1 Rubis-subs-bind SET
81798 e_gw1.4.1229.1 Rubis-subs-bind SET
81880 e_gw1.4.136.1 SET
85776 e_gw1.7.1022.1 SET

General references

Marmorstein, R. 2003. Structure of SET domain proteins: a new twist on histone methylation. Trends Biochem. Sci. 28(2):59-62 PUBMEDID:12575990