Plant Transcription factor database - Universität Potsdam
version: 3.0

Chlamydomonas reinhardtii SNF2 Family

Description

Eisen et al. 1995: The SNF2 family of proteins includes representatives from a variety of species with roles in cellular processes such as transcriptional regulation (e.g. MOT1, SNF2 and BRM), maintenance of chromosome stability during mitosis (e.g. lodestar) and various aspects of processing of DNA damage, including nucleotide excision repair (e.g. RAD16 and ERCC6), recombinational pathways (e.g. RAD54) and post-replication daughter strand gap repair (e.g. RAD5). This family also includes many proteins with no known function. To better characterize this family of proteins we have used molecular phylogenetic techniques to infer evolutionary relationships among the family members. We have divided the SNF2 family into multiple subfamilies, each of which represents what we propose to be a functionally and evolutionarily distinct group. We have then used the subfamily structure to predict the functions of some of the uncharacterized proteins in the SNF2 family. We discuss possible implications of this evolutionary analysis on the general properties and evolution of the SNF2 family.

Members of this family
  SHOULD possess SNF2_N domain
  SHOULD NOT possess AP2 PHD domains

Domain alignments

This family is also present in:

References

There are 17 gene models in this family



Gene modelDescriptionDomains
117345 e_gwW.19.26.1 Helicase_C SNF2_N
13217 fgenesh1_pg.C_scaffold_18000047 Helicase_C PWWP SNF2_N
135484 estExt_gwp_1W.C_110128 HAND Helicase_C ResIII SLIDE SNF2_N
150334 Chlre2_kg.scaffold_34000050 Chromo Helicase_C SNF2_N
152316 Chlre2_kg.scaffold_47000079 Helicase_C SNF2_N zf-C3HC4
168128 fgenesh2_pg.C_scaffold_4000179 Helicase_C SNF2_N zf-C3HC4
169174 fgenesh2_pg.C_scaffold_9000313 Helicase_C SNF2_N
173539 fgenesh2_pg.C_scaffold_22000063 Agenet Helicase_C SNF2_N
177618 fgenesh2_pg.C_scaffold_43000072 HIRAN Helicase_C SNF2_N
180087 fgenesh2_pg.C_scaffold_82000073 Helicase_C SNF2_N
188131 estExt_fgenesh2_pg.C_90026 Chromo Helicase_C SNF2_N
196757 CNA_query Helicase_C SNF2_N
206669 OVA_Chlre2_kg.scaffold_14000083 Helicase_C SNF2_N
206670 OVA_Chlre2_kg.scaffold_8000076 Helicase_C SNF2_N
402783 pasa_Sanger_mRNA26846 AT_hook Helicase_C SNF2_N
6783 fgenesh1_pg.C_scaffold_7000334 Helicase_C SNF2_N
7539 fgenesh1_pg.C_scaffold_3000113 Helicase_C SNF2_N

General references

Bork, P; Koonin, EV. 1993. An expanding family of helicases within the 'DEAD/H' superfamily. Nucleic Acids Res. 21(3):751-2 PUBMEDID:8382805
Eisen, JA; Sweder, KS; Hanawalt, PC. 1995. Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions. Nucleic Acids Res. 23(14):2715-23 PUBMEDID:7651832