Plant Transcription factor database - Universität Potsdam
version: 3.0

Galdieria sulphuraria SNF2 Family


Eisen et al. 1995: The SNF2 family of proteins includes representatives from a variety of species with roles in cellular processes such as transcriptional regulation (e.g. MOT1, SNF2 and BRM), maintenance of chromosome stability during mitosis (e.g. lodestar) and various aspects of processing of DNA damage, including nucleotide excision repair (e.g. RAD16 and ERCC6), recombinational pathways (e.g. RAD54) and post-replication daughter strand gap repair (e.g. RAD5). This family also includes many proteins with no known function. To better characterize this family of proteins we have used molecular phylogenetic techniques to infer evolutionary relationships among the family members. We have divided the SNF2 family into multiple subfamilies, each of which represents what we propose to be a functionally and evolutionarily distinct group. We have then used the subfamily structure to predict the functions of some of the uncharacterized proteins in the SNF2 family. We discuss possible implications of this evolutionary analysis on the general properties and evolution of the SNF2 family.

Members of this family
  SHOULD possess SNF2_N domain
  SHOULD NOT possess AP2 PHD domains

Domain alignments

This family is also present in:


There are 12 gene models in this family

Gene modelDescriptionDomains
Gs05230.1 ref|NP_199166.1|__SNF2 domain-containing protein / helicase domain-containing protein / RING finger domain-containing protein [Arabidopsis thaliana] sp|Q9FIY7|SM3L3_ARATH Putative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin su Helicase_C SNF2_N zf-C3HC4
Gs06540.1 ref|NP_680129.1|__SNF2 domain-containing protein / helicase domain-containing protein / F-box family protein [Arabidopsis thaliana] sp|Q9M1I1|FB304_ARATH F-box protein At3g54455/At3g54460 emb|CAB77566.1| RING finger-like protein [Arabidopsis thaliana] gb| F-box Helicase_C SNF2_N
Gs10500.1 sp|O43065|MOT1_SCHPO__Probable helicase mot1 (TBP-associated factor mot1) (Modifier of transcription 1) emb|CAA21270.2| TATA-binding protein associated factor Mot1 [Schizosaccharomyces pombe] | Symbols: | ATP binding / DNA binding / helicase | chr3:201033 Helicase_C SNF2_N
Gs12420.1 ref|XP_001370692.1|__PREDICTED: similar to SNF2 histone linker PHD RING helicase [Monodelphis domestica] | Symbols: | SNF2 domain-containing protein / helicase domain-containing protein / zinc finger (C3HC4 type RING finger) family protein | chr2:17020613 Helicase_C SNF2_N zf-C3HC4
Gs26570.1 ref|XP_647182.1|__myb domain-containing protein [Dictyostelium discoideum AX4] gb|EAL73272.1| myb domain-containing protein [Dictyostelium discoideum AX4] HSA SNF2_N
Gs28100.1 gb|EAY72175.1|__hypothetical protein OsI_000022 [Oryza sativa (indica cultivar-group)] gb|EAZ10194.1| hypothetical protein OsJ_000019 [Oryza sativa (japonica cultivar-group)] | Symbols: CHR8 | CHR8 (chromatin remodeling 8) Helicase_C SNF2_N
Gs28970.1 ref|XP_001122253.1|__PREDICTED: similar to kismet CG3696-PA, isoform A [Apis mellifera] 5567|protein CHD3-type chromatin remodeling factor PICKLE, putative, expressed Chromo FYRC FYRN Helicase_C SNF2_N
Gs38440.1 ref|XP_001419020.1|__predicted protein [Ostreococcus lucimarinus CCE9901] gb|ABO97313.1| predicted protein [Ostreococcus lucimarinus CCE9901] Helicase_C SLIDE SNF2_N
Gs50140.1 ref|XP_859981.1|__PREDICTED: similar to SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 isoform b isoform 10 [Canis familiaris] | Symbols: | homeotic gene regulator, putative | chr3:1802441-1807290 REVERSE 5050|protein ATP bind HSA Helicase_C SNF2_N
Gs52010.1 gb|AAL73042.1|AF461813_1__chromatin complex subunit A101 [Zea mays] | Symbols: SOM4, SOM1, CHR1, DDM1 | DDM1 (DECREASED DNA METHYLATION 1) Helicase_C SNF2_N
Gs56060.1 ref|XP_001218021.1|__SNF2-family ATP dependent chromatin remodeling factor snf21 [Aspergillus terreus NIH2624] gb|EAU30536.1| SNF2-family ATP dependent chromatin remodeling factor snf21 [Aspergillus terreus NIH2624] Helicase_C SNF2_N
Gs59610.1 ref|XP_413879.2|__PREDICTED: similar to chromodomain helicase DNA binding protein 2 [Gallus gallus] | Symbols: CHR5 | CHR5 (chromatin remodeling 5) Chromo Helicase_C SNF2_N TBC

General references

Bork, P; Koonin, EV. 1993. An expanding family of helicases within the 'DEAD/H' superfamily. Nucleic Acids Res. 21(3):751-2 PUBMEDID:8382805
Eisen, JA; Sweder, KS; Hanawalt, PC. 1995. Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions. Nucleic Acids Res. 23(14):2715-23 PUBMEDID:7651832