Plant Transcription factor database - Universität Potsdam
version: 3.0

Micromonas pusilla CCMP1545 SNF2 Family


Eisen et al. 1995: The SNF2 family of proteins includes representatives from a variety of species with roles in cellular processes such as transcriptional regulation (e.g. MOT1, SNF2 and BRM), maintenance of chromosome stability during mitosis (e.g. lodestar) and various aspects of processing of DNA damage, including nucleotide excision repair (e.g. RAD16 and ERCC6), recombinational pathways (e.g. RAD54) and post-replication daughter strand gap repair (e.g. RAD5). This family also includes many proteins with no known function. To better characterize this family of proteins we have used molecular phylogenetic techniques to infer evolutionary relationships among the family members. We have divided the SNF2 family into multiple subfamilies, each of which represents what we propose to be a functionally and evolutionarily distinct group. We have then used the subfamily structure to predict the functions of some of the uncharacterized proteins in the SNF2 family. We discuss possible implications of this evolutionary analysis on the general properties and evolution of the SNF2 family.

Members of this family
  SHOULD possess SNF2_N domain
  SHOULD NOT possess AP2 PHD domains

Domain alignments

This family is also present in:


There are 22 gene models in this family

Gene modelDescriptionDomains
11467 gw1.5.851.1 SNF2_N
1194 gw1.6.43.1 Helicase_C SNF2_N
12258 e_gw1.1.1156.1 Helicase_C SNF2_N
1244 gw1.15.49.1 Helicase_C SNF2_N
15096 e_gw1.3.163.1 Helicase_C SNF2_N
15861 e_gw1.4.164.1 Helicase_C SNF2_N
16114 e_gw1.4.355.1 SNF2_N
16856 e_gw1.5.131.1 Helicase_C SNF2_N
17189 e_gw1.5.62.1 Helicase_C SNF2_N
18757 e_gw1.7.30.1 Helicase_C SNF2_N
21031 e_gw1.11.41.1 Helicase_C SNF2_N
21039 e_gw1.11.43.1 Chromo Helicase_C SNF2_N
21809 e_gw1.13.423.1 SNF2_N
28265 estExt_Genewise1.C_90264 HAND Helicase_C SLIDE SNF2_N
323 gw1.5.30.1 HIRAN Helicase_C SNF2_N zf-C3HC4
32608 estExt_Genewise1Plus.C_30979 Helicase_C SNF2_N
47521 estExt_fgenesh1_pg.C_60183 Helicase_C SNF2_N
50566 EuGene.0000010790 Helicase_C SNF2_N
50939 EuGene.0000100010 HEAT Helicase_C SNF2_N
54122 EuGene.0000160398 Helicase_C SNF2_N
58044 EuGene.0000050349 HMG_box Helicase_C SNF2_N zf-C3HC4
60694 EuGene.0000090245 Helicase_C SNF2_N

General references

Bork, P; Koonin, EV. 1993. An expanding family of helicases within the 'DEAD/H' superfamily. Nucleic Acids Res. 21(3):751-2 PUBMEDID:8382805
Eisen, JA; Sweder, KS; Hanawalt, PC. 1995. Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions. Nucleic Acids Res. 23(14):2715-23 PUBMEDID:7651832