Plant Transcription factor database - Universität Potsdam
version: 3.0

Micromonas sp. RCC299 SNF2 Family


Eisen et al. 1995: The SNF2 family of proteins includes representatives from a variety of species with roles in cellular processes such as transcriptional regulation (e.g. MOT1, SNF2 and BRM), maintenance of chromosome stability during mitosis (e.g. lodestar) and various aspects of processing of DNA damage, including nucleotide excision repair (e.g. RAD16 and ERCC6), recombinational pathways (e.g. RAD54) and post-replication daughter strand gap repair (e.g. RAD5). This family also includes many proteins with no known function. To better characterize this family of proteins we have used molecular phylogenetic techniques to infer evolutionary relationships among the family members. We have divided the SNF2 family into multiple subfamilies, each of which represents what we propose to be a functionally and evolutionarily distinct group. We have then used the subfamily structure to predict the functions of some of the uncharacterized proteins in the SNF2 family. We discuss possible implications of this evolutionary analysis on the general properties and evolution of the SNF2 family.

Members of this family
  SHOULD possess SNF2_N domain
  SHOULD NOT possess AP2 PHD domains

Domain alignments

This family is also present in:


There are 27 gene models in this family

Gene modelDescriptionDomains
104934 estExt_fgenesh2_kg.C_Chr_090042 HSA Helicase_C SNF2_N
104935 estExt_fgenesh2_kg.C_Chr_090043 HSA Helicase_C SNF2_N
56143 EuGene.0200010520 Helicase_C QLQ SNF2_N
56440 EuGene.0200010817 Helicase_C SNF2_N zf-C3HC4
56506 EuGene.0200010883 Helicase_C SNF2_N zf-CW
58392 EuGene.0500010125 Helicase_C SNF2_N
58407 EuGene.0500010140 Helicase_C SNF2_N zf-RanBP
58699 EuGene.0500010432 Helicase_C SNF2_N
58978 EuGene.0500010711 Helicase_C SNF2_N
59206 EuGene.0600010208 Helicase_C SLIDE SNF2_N
59225 EuGene.0600010227 Helicase_C SNF2_N
59710 EuGene.0600010712 Helicase_C SNF2_N
59808 EuGene.0700010093 HNH Helicase_C SNF2_N
60518 EuGene.0800010086 Helicase_C SNF2_N
60933 EuGene.0800010501 Helicase_C SNF2_N
60953 EuGene.0800010521 Helicase_C SNF2_N
62026 EuGene.1000010363 SNF2_N zf-C3HC4
62843 EuGene.1200010015 HEAT Helicase_C SNF2_N
64101 EuGene.1400010236 Helicase_C SNF2_N zf-C3HC4
64845 EuGene.1600010206 FYRC FYRN Helicase_C SNF2_N
81085 e_gw2.04.45.1 Helicase_C SNF2_N zf-C3HC4
87840 e_gw2.13.60.1 Helicase_C SNF2_N
91017 estExt_Genewise2.C_Chr_060298 Helicase_C SLIDE SNF2_N
96340 fgenesh2_kg.C_Chr_04000024 Helicase_C Rubredoxin SNF2_N
96640 fgenesh2_kg.C_Chr_10000017 Helicase_C SNF2_N
99013 fgenesh2_pg.C_Chr_02000389 Helicase_C SNF2_N
99199 fgenesh2_pg.C_Chr_02000575 HIRAN Helicase_C SNF2_N zf-C3HC4

General references

Bork, P; Koonin, EV. 1993. An expanding family of helicases within the 'DEAD/H' superfamily. Nucleic Acids Res. 21(3):751-2 PUBMEDID:8382805
Eisen, JA; Sweder, KS; Hanawalt, PC. 1995. Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions. Nucleic Acids Res. 23(14):2715-23 PUBMEDID:7651832