Plant Transcription factor database - Universität Potsdam
version: 3.0

Physcomitrella patens SNF2 Family


Eisen et al. 1995: The SNF2 family of proteins includes representatives from a variety of species with roles in cellular processes such as transcriptional regulation (e.g. MOT1, SNF2 and BRM), maintenance of chromosome stability during mitosis (e.g. lodestar) and various aspects of processing of DNA damage, including nucleotide excision repair (e.g. RAD16 and ERCC6), recombinational pathways (e.g. RAD54) and post-replication daughter strand gap repair (e.g. RAD5). This family also includes many proteins with no known function. To better characterize this family of proteins we have used molecular phylogenetic techniques to infer evolutionary relationships among the family members. We have divided the SNF2 family into multiple subfamilies, each of which represents what we propose to be a functionally and evolutionarily distinct group. We have then used the subfamily structure to predict the functions of some of the uncharacterized proteins in the SNF2 family. We discuss possible implications of this evolutionary analysis on the general properties and evolution of the SNF2 family.

Members of this family
  SHOULD possess SNF2_N domain
  SHOULD NOT possess AP2 PHD domains

Domain alignments

This family is also present in:


There are 35 gene models in this family

Gene modelDescriptionDomains
105578 estExt_fgenesh1_pm.C_410017 HIRAN Helicase_C SNF2_N zf-C3HC4
107791 estExt_fgenesh1_pm.C_1970005 Helicase_C SNF2_N
108610 estExt_fgenesh1_pm.C_2930006 Helicase_C SNF2_N
112144 e_gw1.3.67.1 Helicase_C SNF2_N zf-C3HC4
112295 e_gw1.3.78.1 Helicase_C SNF2_N zf-C3HC4
113504 e_gw1.7.55.1 Helicase_C SNF2_N
116197 e_gw1.15.318.1 F-box Helicase_C SNF2_N zf-CW
119270 e_gw1.28.78.1 Helicase_C SNF2_N
125588 e_gw1.55.28.1 Helicase_C ResIII SNF2_N
132084 e_gw1.93.19.1 Chromo Helicase_C SNF2_N
140579 e_gw1.168.9.1 Helicase_C SNF2_N
147229 e_gw1.256.4.1 Helicase_C SNF2_N
147434 e_gw1.259.47.1 Helicase_C SNF2_N
148543 e_gw1.279.53.1 Helicase_C SNF2_N
160727 estExt_fgenesh1_pg.C_250145 Bromodomain Helicase_C SNF2_N
168107 estExt_fgenesh1_pg.C_1660051 Chromo Helicase_C ResIII SNF2_N
172564 estExt_fgenesh1_pg.C_3600020 AT_hook Helicase_C ResIII SNF2_N
184534 estExt_gwp_gw1.C_740149 HEAT Helicase_C SNF2_N
189373 estExt_gwp_gw1.C_1320001 Helicase_C SNF2_N zf-C3HC4
20076 gw1.34.27.1 Helicase_C SNF2_N
210776 estExt_Genewise1.C_650125 Helicase_C SNF2_N
21176 gw1.212.59.1 Helicase_C SNF2_N
211797 estExt_Genewise1.C_730104 Helicase_C SNF2_N zf-C3HC4
216086 estExt_Genewise1.C_1230104 HAND Helicase_C ResIII SLIDE SNF2_N
216975 estExt_Genewise1.C_1360060 HAND Helicase_C SLIDE SNF2_N
30018 gw1.452.26.1 HSA Helicase_C ResIII SNF2_N
34 gw1.317.1.1 Chromo Helicase_C SNF2_N
40536 gw1.54.225.1 Helicase_C SNF2_N
40675 gw1.155.65.1 Helicase_C ResIII SNF2_N
67427 fgenesh1_pg.scaffold_14000215 Helicase_C SNF2_N zf-C3HC4
71851 fgenesh1_pg.scaffold_34000116 Helicase_C SNF2_N
77632 fgenesh1_pg.scaffold_66000079 Helicase_C SNF2_N
80235 fgenesh1_pg.scaffold_84000145 Helicase_C SNF2_N
87464 fgenesh1_pg.scaffold_158000020 Bromodomain Helicase_C SNF2_N
95912 fgenesh1_pg.scaffold_291000007 Chromo Helicase_C SNF2_N

General references

Bork, P; Koonin, EV. 1993. An expanding family of helicases within the 'DEAD/H' superfamily. Nucleic Acids Res. 21(3):751-2 PUBMEDID:8382805
Eisen, JA; Sweder, KS; Hanawalt, PC. 1995. Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions. Nucleic Acids Res. 23(14):2715-23 PUBMEDID:7651832