Plant Transcription factor database - Universität Potsdam
version: 3.0

Sorghum bicolor SNF2 Family


Eisen et al. 1995: The SNF2 family of proteins includes representatives from a variety of species with roles in cellular processes such as transcriptional regulation (e.g. MOT1, SNF2 and BRM), maintenance of chromosome stability during mitosis (e.g. lodestar) and various aspects of processing of DNA damage, including nucleotide excision repair (e.g. RAD16 and ERCC6), recombinational pathways (e.g. RAD54) and post-replication daughter strand gap repair (e.g. RAD5). This family also includes many proteins with no known function. To better characterize this family of proteins we have used molecular phylogenetic techniques to infer evolutionary relationships among the family members. We have divided the SNF2 family into multiple subfamilies, each of which represents what we propose to be a functionally and evolutionarily distinct group. We have then used the subfamily structure to predict the functions of some of the uncharacterized proteins in the SNF2 family. We discuss possible implications of this evolutionary analysis on the general properties and evolution of the SNF2 family.

Members of this family
  SHOULD possess SNF2_N domain
  SHOULD NOT possess AP2 PHD domains

Domain alignments

This family is also present in:


There are 38 gene models in this family

Gene modelDescriptionDomains
143107 estExt_fgenesh1_pm.C_chr_30385 Helicase_C SNF2_N
144711 estExt_fgenesh1_pm.C_chr_40875 HSA Helicase_C ResIII SNF2_N
145412 estExt_fgenesh1_pm.C_chr_60360 Helicase_C SNF2_N
4749144 estExt_Genewise1.C_chr_29355 Helicase_C SNF2_N zf-C3HC4
4754753 estExt_Genewise1.C_chr_311162 F-box Helicase_C SNF2_N zf-CW
4756455 estExt_Genewise1.C_chr_46057 HIRAN Helicase_C SNF2_N zf-C3HC4
4785513 e_gw1.2.19536.1 Helicase_C SNF2_N
4787057 e_gw1.2.150.1 Helicase_C SNF2_N
4792841 e_gw1.2.19797.1 HIRAN Helicase_C SNF2_N zf-C3HC4
4793535 e_gw1.2.20146.1 Helicase_C ResIII SNF2_N
4816526 e_gw1.4.17274.1 Helicase_C SNF2_N
4833008 e_gw1.6.16133.1 Helicase_C SNF2_N
4839144 e_gw1.7.114.1 Helicase_C SNF2_N
4854110 e_gw1.9.13661.1 Helicase_C SNF2_N
4855583 e_gw1.9.16112.1 HEAT Helicase_C SNF2_N
4859410 e_gw1.10.2205.1 Helicase_C SNF2_N
4868945 estExt_Genewise1Plus.C_chr_13551 Helicase_C SNF2_N
4869378 estExt_Genewise1Plus.C_chr_14425 Helicase_C SNF2_N
4870786 estExt_Genewise1Plus.C_chr_19129 Helicase_C SNF2_N
4872321 estExt_Genewise1Plus.C_chr_111438 Helicase_C SNF2_N
4872964 estExt_Genewise1Plus.C_chr_112499 Helicase_C SNF2_N
4887201 estExt_Genewise1Plus.C_chr_60822 HIRAN Helicase_C SNF2_N zf-C3HC4
4889164 estExt_Genewise1Plus.C_chr_67817 Helicase_C SNF2_N zf-C3HC4
4976538 fgenesh1_pg.C_chr_3003653 Helicase_C ResIII SNF2_N
4977242 fgenesh1_pg.C_chr_4000075 SNF2_N
5003426 estExt_fgenesh1_pg.C_chr_40088 Helicase_C QLQ SNF2_N
5007548 estExt_fgenesh1_pg.C_chr_70592 Helicase_C SNF2_N
5010289 estExt_fgenesh1_pg.C_chr_100011 SNF2_N
5010592 estExt_fgenesh1_pg.C_chr_100595 Chromo DUF1086 DUF1087 Helicase_C ResIII SNF2_N
5034608 Sb02g038340 HNH Helicase_C SNF2_N
5037362 Sb04g000807 SNF2_N
5042814 Sb06g034160 Helicase_C SNF2_N
5048252 Sb01g009790 Helicase_C SNF2_N
5052111 Sb02g040560 Helicase_C SNF2_N
5052190 Sb02g041910 Chromo Helicase_C SNF2_N
5053112 Sb03g014780 HAND Helicase_C SLIDE SNF2_N
5053814 Sb03g036380 Helicase_C SNF2_N zf-C3HC4
5060089 Sb09g003430 Helicase_C ResIII SNF2_N

General references

Bork, P; Koonin, EV. 1993. An expanding family of helicases within the 'DEAD/H' superfamily. Nucleic Acids Res. 21(3):751-2 PUBMEDID:8382805
Eisen, JA; Sweder, KS; Hanawalt, PC. 1995. Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions. Nucleic Acids Res. 23(14):2715-23 PUBMEDID:7651832