Plant Transcription factor database - Universität Potsdam
version: 3.0

Arabidopsis lyrata SRS Family


Fridborg et al. 2001: The current model of gibberellin (GA) signal transduction is based on a derepressible system and a number of candidate negative regulators have been identified in Arabidopsis. We previously have reported the identification of the Arabidopsis gene SHORT INTERNODES (SHI) that causes suppression of GA responses when constitutively activated. In this paper, we show by using reporter gene analysis that the SHI gene is expressed in young organs, e.g. shoot apices and root tips. The model predicts a suppressor of GA responses to be active in these tissues to prevent premature growth or development. To study the effect of SHI on GA signaling, we used a functional assay that measures effects of signaling components on a well-defined GA response; the up-regulation of alpha-amylase in barley (Hordeum vulgare) aleurones in response to GA treatment. We found that SHI was able to specifically block the activity of a high-isoelectric point alpha-amylase promoter following GA(3) treatment, which further supports that SHI is a suppressor of GA responses. We have identified two putative loss-of-function insertion alleles of SHI and lines homozygous for either of the new alleles show no phenotypic deviations from wild type. Because SHI belongs to a gene family consisting of nine members, we suggest that SHI and the SHI-related genes are functionally redundant. We also show that a functional ERECTA allele is able to partly suppress the dwarfing effect of the shi gain-of-function mutation, suggesting that the erecta mutation harbored by the Landsberg erecta ecotype is an enhancer of the shi dwarf phenotype.

Members of this family
  SHOULD possess DUF702 domain

Domain alignments

This family is also present in:


There are 9 gene models in this family

Gene modelDescriptionDomains
319764 fgenesh1_pm.C_scaffold_3002780 DUF702
319991 fgenesh1_pm.C_scaffold_4000048 DUF702
472205 fgenesh2_kg.1__2159__AT1G19790.1 DUF702
476700 fgenesh2_kg.2__1830__AT1G75520.1 DUF702
485843 fgenesh2_kg.5__1835__AT3G54430.1 DUF702
488079 fgenesh2_kg.6__1213__AT5G12330.3 DUF702
491005 fgenesh2_kg.7__438__AT4G36260.1 DUF702
906453 scaffold_502157.1 DUF702
920093 scaffold_803493.1 DUF702

General references

Fridborg, I; Kuusk, S; Robertson, M; Sundberg, E. 2001. The Arabidopsis protein SHI represses gibberellin responses in Arabidopsis and barley. Plant Physiol. 127(3):937-48 PUBMEDID:11706176