Plant Transcription factor database - Universität Potsdam
version: 3.0

Zea mays SRS Family


Fridborg et al. 2001: The current model of gibberellin (GA) signal transduction is based on a derepressible system and a number of candidate negative regulators have been identified in Arabidopsis. We previously have reported the identification of the Arabidopsis gene SHORT INTERNODES (SHI) that causes suppression of GA responses when constitutively activated. In this paper, we show by using reporter gene analysis that the SHI gene is expressed in young organs, e.g. shoot apices and root tips. The model predicts a suppressor of GA responses to be active in these tissues to prevent premature growth or development. To study the effect of SHI on GA signaling, we used a functional assay that measures effects of signaling components on a well-defined GA response; the up-regulation of alpha-amylase in barley (Hordeum vulgare) aleurones in response to GA treatment. We found that SHI was able to specifically block the activity of a high-isoelectric point alpha-amylase promoter following GA(3) treatment, which further supports that SHI is a suppressor of GA responses. We have identified two putative loss-of-function insertion alleles of SHI and lines homozygous for either of the new alleles show no phenotypic deviations from wild type. Because SHI belongs to a gene family consisting of nine members, we suggest that SHI and the SHI-related genes are functionally redundant. We also show that a functional ERECTA allele is able to partly suppress the dwarfing effect of the shi gain-of-function mutation, suggesting that the erecta mutation harbored by the Landsberg erecta ecotype is an enhancer of the shi dwarf phenotype.

Members of this family
  SHOULD possess DUF702 domain

Domain alignments

This family is also present in:


There are 18 gene models in this family

Gene modelDescriptionDomains
GRMZM2G017606_P01 DUF702
GRMZM2G034042_P01 DUF702
GRMZM2G042407_P01 DUF702
GRMZM2G042407_P02 DUF702
GRMZM2G054981_P01 DUF702
GRMZM2G077752_P01 DUF702
GRMZM2G080295_P01 DUF702
GRMZM2G097683_P01 DUF702
GRMZM2G106852_P01 DUF702
GRMZM2G108798_P01 DUF702
GRMZM2G114273_P01 DUF702
GRMZM2G135783_P01 DUF702
GRMZM2G135783_P02 DUF702
GRMZM2G149425_P01 DUF702
GRMZM2G160190_P01 DUF702
GRMZM2G160190_P03 DUF702
GRMZM2G163613_P01 DUF702
GRMZM2G179021_P01 DUF702

General references

Fridborg, I; Kuusk, S; Robertson, M; Sundberg, E. 2001. The Arabidopsis protein SHI represses gibberellin responses in Arabidopsis and barley. Plant Physiol. 127(3):937-48 PUBMEDID:11706176