Plant Transcription factor database - Universität Potsdam
version: 3.0

Oryza sativa subsp. indica TRAF Family


Stogios et al. 2005:The BTB domain (also known as the POZ domain) is a versatile protein-protein interaction motif that participates in a wide range of cellular functions, including transcriptional regulation, cytoskeleton dynamics, ion channel assembly and gating, and targeting proteins for ubiquitination. Several BTB domain structures have been experimentally determined, revealing a highly conserved core structure. The BTB domain is typically found as a single copy in proteins that contain only one or two other types of domain, and this defines the BTB-zinc finger (BTB-ZF), BTB-BACK-kelch (BBK), voltage-gated potassium channel T1 (T1-Kv), MATH-BTB, BTB-NPH3 and BTB-BACK-PHR (BBP) families of proteins, among others. BTB-ZF proteins are also known as the POK (POZ and Krüppel zinc finger) proteins. Many members of this large family have been characterized as important transcriptional factors, and several are implicated in development and cancer, most notably BCL6, leukemia/lymphoma related factor (LRF)/Pokemon, PLZF, hypermethylated in cancer (HIC)1 and Myc interacting zinc finger (MIZ)1.

Members of this family
  SHOULD possess BTB domain
  SHOULD NOT possess BACK MATH NPH3 zf-TAZ domains

Domain alignments

This family is also present in:


There are 90 gene models in this family

Gene modelDescriptionDomains
OsIBCD004235 Chr01_6478,594,,,1,594, BTB
OsIBCD004409 Chr01_6727,2460,,,1,2460, BTB
OsIBCD004505 Chr01_6870,1521,,,1,1521, Ank BTB
OsIBCD011480 Chr03_4629,1770,,,1,1770, Ank BTB
OsIBCD011786 Chr03_5112,825,,,1,825, BTB
OsIBCD014382 Chr04_2874,930,,,1,930, BTB
OsIBCD014388 Chr04_2884,999,,,1,999, BTB
OsIBCD014738 Chr04_3368,1068,,,1,1068, BTB
OsIBCD015654 Chr04_4686,1131,,,1,1131, BTB
OsIBCD015664 Chr04_4697,924,,,1,924, BTB
OsIBCD017584 Chr05_2562,1971,,,1,1971, BTB
OsIBCD017920 Chr05_3078,2115,,,1,2115, Arm BTB HEAT
OsIBCD019930 Chr06_1250,579,,,1,579, BTB
OsIBCD019931 Chr06_1251,819,,,1,819, BTB
OsIBCD020361 Chr06_1954,1707,,,1,1707, BTB
OsIBCD020842 Chr06_2912,1611,,,1,1611, BTB
OsIBCD021727 Chr06_4346,834,,,1,834, BTB
OsIBCD021767 Chr06_4405,3411,,,1,3411, BTB
OsIBCD022942 Chr07_1393,741,,,1,741, BTB
OsIBCD023771 Chr07_2912,897,,,1,897, BTB
OsIBCD024735 Chr08_34,1020,,,1,1020, BTB
OsIBCD024883 Chr08_265,984,,,1,984, BTB
OsIBCD025282 Chr08_881,1197,,,1,1197, BTB
OsIBCD025385 Chr08_1057,1770,,,1,1770, BTB
OsIBCD025477 Chr08_1234,1194,,,1,1194, BTB
OsIBCD025484 Chr08_1247,1011,,,1,1011, BTB
OsIBCD025486 Chr08_1249,948,,,1,948, BTB
OsIBCD025497 Chr08_1268,1707,,,1,1707, BTB
OsIBCD026955 Chr08_3875,1056,,,1,1056, BTB
OsIBCD027094 Chr08_4082,735,,,1,735, BTB
OsIBCD027095 Chr08_4083,744,,,1,744, BTB
OsIBCD027135 Chr08_4156,1416,,,1,1416, BTB
OsIBCD027136 Chr08_4157,1101,,,1,1101, BTB
OsIBCD027137 Chr08_4158,1032,,,1,1032, BTB
OsIBCD027138 Chr08_4160,819,,,1,819, BTB
OsIBCD027688 Chr09_459,1032,,,1,1032, BTB
OsIBCD030625 Chr10_2006,1083,,,1,1083, BTB
OsIBCD030628 Chr10_2011,1287,,,1,1287, BTB
OsIBCD030630 Chr10_2017,909,,,1,909, BTB
OsIBCD030634 Chr10_2025,1236,,,1,1236, BTB
OsIBCD030635 Chr10_2030,621,,,1,621, BTB
OsIBCD030637 Chr10_2036,921,,,1,921, BTB
OsIBCD030644 Chr10_2046,1557,,,1,1557, BTB
OsIBCD030645 Chr10_2047,735,,,1,735, BTB
OsIBCD030647 Chr10_2049,678,,,1,678, BTB
OsIBCD030650 Chr10_2053,975,,,1,975, BTB
OsIBCD030652 Chr10_2055,1095,,,1,1095, BTB
OsIBCD030674 Chr10_2106,6030,,,1,6030, BTB RVT_2 rve zf-CCHC
OsIBCD030681 Chr10_2117,567,,,1,567, BTB
OsIBCD030687 Chr10_2131,1767,,,1,1767, BTB
OsIBCD030692 Chr10_2140,906,,,1,906, BTB
OsIBCD031619 Chr11_49,807,,,1,807, BTB
OsIBCD031803 Chr11_313,1482,,,1,1482, Ank BTB
OsIBCD031811 Chr11_323,1485,,,1,1485, Ank BTB
OsIBCD033446 Chr11_3061,1233,,,1,1233, BTB
OsIBCD033531 Chr11_3189,1077,,,1,1077, BTB
OsIBCD033533 Chr11_3192,822,,,1,822, BTB
OsIBCD033835 Chr12_135,804,,,1,804, BTB
OsIBCD038269 Chr02_5224,390,,,1,390, BTB
OsIBCD039885 Chr04_1415,1059,,,1,1059, BTB
OsIBCD040144 Chr04_2870,1116,,,1,1116, BTB
OsIBCD040148 Chr04_2878,1140,,,1,1140, BTB
OsIBCD040506 Chr04_4698,1152,,,1,1152, BTB
OsIBCD040508 Chr04_4700,1113,,,1,1113, BTB
OsIBCD040557 Chr04_4993,1062,,,1,1062, BTB
OsIBCD041868 Chr06_1400,1059,,,1,1059, BTB
OsIBCD043434 Chr08_260,1125,,,1,1125, BTB
OsIBCD043436 Chr08_262,1065,,,1,1065, BTB
OsIBCD043437 Chr08_263,1047,,,1,1047, BTB
OsIBCD043620 Chr08_1241,1161,,,1,1161, BTB
OsIBCD043621 Chr08_1242,1068,,,1,1068, BTB
OsIBCD043623 Chr08_1246,876,,,1,876, BTB
OsIBCD044148 Chr08_4131,504,,,1,504, BTB
OsIBCD044153 Chr08_4147,1068,,,1,1068, BTB
OsIBCD044154 Chr08_4148,858,,,1,858, BTB
OsIBCD044155 Chr08_4149,990,,,1,990, BTB
OsIBCD044160 Chr08_4163,1050,,,1,1050, BTB
OsIBCD044462 Chr09_1327,1152,,,1,1152, BTB
OsIBCD044463 Chr09_1330,1023,,,1,1023, BTB
OsIBCD045256 Chr10_2007,1119,,,1,1119, BTB
OsIBCD045262 Chr10_2020,858,,,1,858, BTB
OsIBCD045265 Chr10_2028,1173,,,1,1173, BTB
OsIBCD045266 Chr10_2029,498,,,1,498, BTB
OsIBCD045270 Chr10_2035,1236,,,1,1236, BTB
OsIBCD045978 Chr11_1791,1125,,,1,1125, BTB
OsIBCD046198 Chr11_3055,1125,,,1,1125, BTB
OsIBCD046221 Chr11_3145,1047,,,1,1047, BTB
OsIBCD046234 Chr11_3191,834,,,1,834, BTB
OsIBCD046240 Chr11_3210,486,,,1,486, BTB
OsIBSD048355 Supscaffold476_2,693,,,1,693, BTB

General references

Deweindt, C; Albagli, O; Bernardin, F; Dhordain, P; Quief, S; Lantoine, D; Kerckaert, JP; Leprince, D. 1995. The LAZ3/BCL6 oncogene encodes a sequence-specific transcriptional inhibitor: a novel function for the BTB/POZ domain as an autonomous repressing domain. Cell Growth Differ. 6(12):1495-503 PUBMEDID:9019154
Stogios, PJ; Downs, GS; Jauhal, JJ; Nandra, SK; Privé, GG. 2005. Sequence and structural analysis of BTB domain proteins. Genome Biol. 6(10):R82 PUBMEDID:16207353