Plant Transcription factor database - Universität Potsdam
version: 3.0

Zea mays TRAF Family

Description

Stogios et al. 2005:The BTB domain (also known as the POZ domain) is a versatile protein-protein interaction motif that participates in a wide range of cellular functions, including transcriptional regulation, cytoskeleton dynamics, ion channel assembly and gating, and targeting proteins for ubiquitination. Several BTB domain structures have been experimentally determined, revealing a highly conserved core structure. The BTB domain is typically found as a single copy in proteins that contain only one or two other types of domain, and this defines the BTB-zinc finger (BTB-ZF), BTB-BACK-kelch (BBK), voltage-gated potassium channel T1 (T1-Kv), MATH-BTB, BTB-NPH3 and BTB-BACK-PHR (BBP) families of proteins, among others. BTB-ZF proteins are also known as the POK (POZ and Krüppel zinc finger) proteins. Many members of this large family have been characterized as important transcriptional factors, and several are implicated in development and cancer, most notably BCL6, leukemia/lymphoma related factor (LRF)/Pokemon, PLZF, hypermethylated in cancer (HIC)1 and Myc interacting zinc finger (MIZ)1.

Members of this family
  SHOULD possess BTB domain
  SHOULD NOT possess BACK MATH NPH3 zf-TAZ domains

Domain alignments

This family is also present in:

References

There are 66 gene models in this family



Gene modelDescriptionDomains
GRMZM2G004161_P01 BTB
GRMZM2G004161_P03 BTB
GRMZM2G004523_P03 BTB
GRMZM2G009724_P01 BTB
GRMZM2G009724_P02 BTB
GRMZM2G010794_P01 BTB
GRMZM2G010794_P02 BTB
GRMZM2G010794_P03 BTB
GRMZM2G017404_P01 BTB
GRMZM2G019542_P01 BTB
GRMZM2G022606_P02 Ank BTB
GRMZM2G026556_P01 Ank BTB
GRMZM2G038691_P01 BTB
GRMZM2G038691_P02 BTB
GRMZM2G040465_P01 BTB
GRMZM2G040509_P01 BTB
GRMZM2G041963_P01 BTB
GRMZM2G046342_P01 BTB
GRMZM2G046342_P03 BTB
GRMZM2G046342_P04 BTB
GRMZM2G048192_P01 BTB
GRMZM2G052985_P01 BTB
GRMZM2G060723_P01 Ank BTB
GRMZM2G060723_P02 BTB
GRMZM2G060765_P05 BTB
GRMZM2G066038_P01 BTB
GRMZM2G071885_P01 BTB
GRMZM2G076462_P01 BTB
GRMZM2G077197_P01 Ank BTB
GRMZM2G077428_P01 BTB
GRMZM2G077951_T01_P01 BTB
GRMZM2G088086_P01 BTB
GRMZM2G095510_P01 BTB
GRMZM2G096819_P01 Ank BTB
GRMZM2G096819_P02 BTB
GRMZM2G098227_P01 Arm BTB
GRMZM2G100946_P01 Arm BTB HEAT
GRMZM2G103251_P01 BTB
GRMZM2G103314_P01 BTB
GRMZM2G103314_P02 BTB Thiolase_C
GRMZM2G104338_P01 BTB
GRMZM2G109738_P01 BTB
GRMZM2G120928_P01 BTB
GRMZM2G120930_P01 BTB
GRMZM2G121115_P01 BTB
GRMZM2G121115_P03 BTB
GRMZM2G128485_P02 BTB
GRMZM2G128485_P03 BTB
GRMZM2G128623_P01 BTB
GRMZM2G130505_P01 BTB
GRMZM2G130505_P03 BTB
GRMZM2G130505_P04 BTB
GRMZM2G136754_P01 Ank BTB
GRMZM2G143782_P01 BTB
GRMZM2G160892_P01 BTB
GRMZM2G161569_P01 BTB
GRMZM2G161610_P01 BTB
GRMZM2G163671_P01 BTB
GRMZM2G163671_P03 BTB
GRMZM2G164669_P01 Ank BTB
GRMZM2G171951_P01 BTB
GRMZM2G172114_P01 Ank BTB
GRMZM2G174144_P01 Arm BTB
GRMZM2G178375_P01 Arm BTB HEAT
GRMZM2G178684_P01 BTB
GRMZM2G180162_P01 BTB

General references

Deweindt, C; Albagli, O; Bernardin, F; Dhordain, P; Quief, S; Lantoine, D; Kerckaert, JP; Leprince, D. 1995. The LAZ3/BCL6 oncogene encodes a sequence-specific transcriptional inhibitor: a novel function for the BTB/POZ domain as an autonomous repressing domain. Cell Growth Differ. 6(12):1495-503 PUBMEDID:9019154
Stogios, PJ; Downs, GS; Jauhal, JJ; Nandra, SK; Privé, GG. 2005. Sequence and structural analysis of BTB domain proteins. Genome Biol. 6(10):R82 PUBMEDID:16207353