Plant Transcription factor database - Universität Potsdam
version: 3.0

Arabidopsis lyrata Trihelix Family

Description

Smalle et al. 1998: GT-2 is a plant transcriptional activator that contains two separate, but similar, trihelix DNA-binding domains. GT-1 is similar to GT-2, although it contains only one of such domains. cDNAs that encode GT-2 were isolated from rice (OS-GT2) and Arabidopsis (AT-GT2). Evidence is presented for the existence of an Arabidopsis gene family that is structurally related to AT-GT2. Two members of this GT2-like family, AT-GTL1 and AT-GTL2, have been isolated and characterized. Their sequences suggest that they evolved by a recent gene duplication event. Both AT-GT2 and AT-GTL genes contain an intron in the amino-terminal trihelix motif, indicating that this DNA-binding domain resulted from exon shuffling. RNA gel blot analysis using AT-GTL1 as a probe revealed four transcripts in the aerial part of the plant. All mRNA levels were significantly higher in siliques, suggesting that this gene family may function in fruit and/or seed development. To date, DNA-binding proteins characterized by the trihelix motif have been described only in plants, and may therefore be involved in plant-specific processes. Our results show that in Arabidopsis thaliana, the trihelix motif is not restricted to the GT-1 and GT-2 DNA-binding proteins.

Members of this family
  SHOULD possess trihelix domain

Domain alignments

This family is also present in:

References

There are 24 gene models in this family



Gene modelDescriptionDomains
317804 fgenesh1_pm.C_scaffold_3000820 trihelix AA_kinase
341138 fgenesh1_pg.C_scaffold_3000901 trihelix
341554 fgenesh1_pg.C_scaffold_3001317 trihelix
358545 fgenesh1_pg.C_scaffold_8002332 trihelix Lactamase_B RMMBL
473497 fgenesh2_kg.1__3451__AT1G33240.1 trihelix
474535 fgenesh2_kg.1__4489__AT1G54060.1 trihelix
478832 fgenesh2_kg.3__1533__AT3G14180.1 trihelix
480003 fgenesh2_kg.3__2704__AT3G24860.1 trihelix
483602 fgenesh2_kg.4__2662__AT2G44730.1 trihelix MADF_DNA_bdg
484361 fgenesh2_kg.5__353__AT3G25990.1 trihelix
485840 fgenesh2_kg.5__1832__AT3G54390.1 trihelix
486315 fgenesh2_kg.5__2307__AT3G58630.1 trihelix
486939 fgenesh2_kg.6__73__AT5G01380.1 trihelix
487148 fgenesh2_kg.6__282__AT5G03680.1 trihelix
487349 fgenesh2_kg.6__483__AT5G05550.1 trihelix
489647 fgenesh2_kg.6__2781__AT5G28300.1 trihelix
870219 Al_scaffold_0004_2382 trihelix
883757 Al_scaffold_0008_21 trihelix
888711 scaffold_101505.1 trihelix
895569 scaffold_202643.1 trihelix
895570 scaffold_202644.1 trihelix
897310 scaffold_301280.1 trihelix
899026 scaffold_302996.1 trihelix
902429 scaffold_401930.1 trihelix

General references

Nagano, Y. 2000. Several features of the GT-factor trihelix domain resemble those of the Myb DNA-binding domain. Plant Physiol. 124(2):491-4 PUBMEDID:11027698
Nagano, Y; Inaba, T; Furuhashi, H; Sasaki, Y. 2001. Trihelix DNA-binding protein with specificities for two distinct cis-elements: both important for light down-regulated and dark-inducible gene expression in higher plants. J. Biol. Chem. 276(25):22238-43 PUBMEDID:11301338
Smalle, J; Kurepa, J; Haegman, M; Gielen, J; Van Montagu, M; Van Der Straeten, D. 1998. The trihelix DNA-binding motif in higher plants is not restricted to the transcription factors GT-1 and GT-2. Proc. Natl. Acad. Sci. U.S.A. 95(6):3318-22 PUBMEDID:9501260
Zhou, DX. 1999. Regulatory mechanism of plant gene transcription by GT-elements and GT-factors. Trends Plant Sci 4(6):210-214 PUBMEDID:10366876