Plant Transcription factor database - Universität Potsdam
version: 3.0

Oryza sativa subsp. indica Trihelix Family

Description

Smalle et al. 1998: GT-2 is a plant transcriptional activator that contains two separate, but similar, trihelix DNA-binding domains. GT-1 is similar to GT-2, although it contains only one of such domains. cDNAs that encode GT-2 were isolated from rice (OS-GT2) and Arabidopsis (AT-GT2). Evidence is presented for the existence of an Arabidopsis gene family that is structurally related to AT-GT2. Two members of this GT2-like family, AT-GTL1 and AT-GTL2, have been isolated and characterized. Their sequences suggest that they evolved by a recent gene duplication event. Both AT-GT2 and AT-GTL genes contain an intron in the amino-terminal trihelix motif, indicating that this DNA-binding domain resulted from exon shuffling. RNA gel blot analysis using AT-GTL1 as a probe revealed four transcripts in the aerial part of the plant. All mRNA levels were significantly higher in siliques, suggesting that this gene family may function in fruit and/or seed development. To date, DNA-binding proteins characterized by the trihelix motif have been described only in plants, and may therefore be involved in plant-specific processes. Our results show that in Arabidopsis thaliana, the trihelix motif is not restricted to the GT-1 and GT-2 DNA-binding proteins.

Members of this family
  SHOULD possess trihelix domain

Domain alignments

This family is also present in:

References

There are 22 gene models in this family



Gene modelDescriptionDomains
OsIBCD004367 Chr01_6673,885,,,1,885, trihelix
OsIBCD004732 Chr02_40,2136,,,1,2136, trihelix
OsIBCD006762 Chr02_3334,2616,,,1,2616, trihelix Lactamase_B RMMBL
OsIBCD007412 Chr02_4304,1713,,,1,1713, trihelix
OsIBCD008623 Chr03_137,1947,,,1,1947, trihelix
OsIBCD008624 Chr03_138,345,,,1,345, trihelix
OsIBCD009784 Chr03_1748,717,,,1,717, trihelix
OsIBCD009785 Chr03_1749,807,,,1,807, trihelix
OsIBCD014233 Chr04_2652,1428,,,1,1428, trihelix AA_kinase
OsIBCD014765 Chr04_3400,1338,,,1,1338, trihelix Myb_DNA-binding
OsIBCD015128 Chr04_3924,2283,,,1,2283, trihelix
OsIBCD015477 Chr04_4454,834,,,1,834, trihelix
OsIBCD016318 Chr05_264,933,,,1,933, trihelix
OsIBCD018870 Chr05_4475,960,,,1,960, trihelix
OsIBCD028282 Chr09_1545,3930,,,1,3930, trihelix LRR_1 NB-ARC
OsIBCD031201 Chr10_2898,2079,,,1,2079, trihelix
OsIBCD036704 Chr01_4539,999,,,1,999, trihelix
OsIBCD036782 Chr01_4905,1056,,,1,1056, trihelix
OsIBCD037915 Chr02_3539,1257,,,1,1257, trihelix
OsIBCD041458 Chr05_4472,1026,,,1,1026, trihelix
OsIBCD044861 Chr09_3213,1014,,,1,1014, trihelix
OsIBCD045571 Chr10_3305,1011,,,1,1011, trihelix

General references

Nagano, Y. 2000. Several features of the GT-factor trihelix domain resemble those of the Myb DNA-binding domain. Plant Physiol. 124(2):491-4 PUBMEDID:11027698
Nagano, Y; Inaba, T; Furuhashi, H; Sasaki, Y. 2001. Trihelix DNA-binding protein with specificities for two distinct cis-elements: both important for light down-regulated and dark-inducible gene expression in higher plants. J. Biol. Chem. 276(25):22238-43 PUBMEDID:11301338
Smalle, J; Kurepa, J; Haegman, M; Gielen, J; Van Montagu, M; Van Der Straeten, D. 1998. The trihelix DNA-binding motif in higher plants is not restricted to the transcription factors GT-1 and GT-2. Proc. Natl. Acad. Sci. U.S.A. 95(6):3318-22 PUBMEDID:9501260
Zhou, DX. 1999. Regulatory mechanism of plant gene transcription by GT-elements and GT-factors. Trends Plant Sci 4(6):210-214 PUBMEDID:10366876