Plant Transcription factor database - Universität Potsdam
version: 3.0

Populus trichocarpa Trihelix Family

Description

Smalle et al. 1998: GT-2 is a plant transcriptional activator that contains two separate, but similar, trihelix DNA-binding domains. GT-1 is similar to GT-2, although it contains only one of such domains. cDNAs that encode GT-2 were isolated from rice (OS-GT2) and Arabidopsis (AT-GT2). Evidence is presented for the existence of an Arabidopsis gene family that is structurally related to AT-GT2. Two members of this GT2-like family, AT-GTL1 and AT-GTL2, have been isolated and characterized. Their sequences suggest that they evolved by a recent gene duplication event. Both AT-GT2 and AT-GTL genes contain an intron in the amino-terminal trihelix motif, indicating that this DNA-binding domain resulted from exon shuffling. RNA gel blot analysis using AT-GTL1 as a probe revealed four transcripts in the aerial part of the plant. All mRNA levels were significantly higher in siliques, suggesting that this gene family may function in fruit and/or seed development. To date, DNA-binding proteins characterized by the trihelix motif have been described only in plants, and may therefore be involved in plant-specific processes. Our results show that in Arabidopsis thaliana, the trihelix motif is not restricted to the GT-1 and GT-2 DNA-binding proteins.

Members of this family
  SHOULD possess trihelix domain

Domain alignments

This family is also present in:

References

There are 43 gene models in this family



Gene modelDescriptionDomains
175065 gw1.I.3665.1 trihelix
177109 gw1.I.5709.1 trihelix
178438 gw1.I.7038.1 trihelix
178520 gw1.I.7120.1 trihelix
180663 gw1.I.9263.1 trihelix
181054 gw1.I.9654.1 trihelix
204916 gw1.V.317.1 trihelix
232801 gw1.XI.781.1 trihelix
252988 gw1.XV.2424.1 trihelix
264764 gw1.118.252.1 trihelix Myb_DNA-binding
276604 gw1.185.36.1 trihelix
413008 gw1.III.111.1 trihelix
413413 gw1.III.516.1 trihelix
548101 eugene3.00010542 trihelix
551322 eugene3.00020637 trihelix
551971 eugene3.00021286 trihelix
553172 eugene3.00002487 trihelix
553703 eugene3.00030336 trihelix
554278 eugene3.00030911 trihelix
560102 eugene3.00060061 trihelix
560923 eugene3.00060882 trihelix
561592 eugene3.00061551 trihelix
564061 eugene3.00080656 trihelix
567243 eugene3.00101801 trihelix
571019 eugene3.00130383 trihelix
577994 eugene3.00180218 trihelix
591748 eugene3.00400093 trihelix
655813 grail3.0090017601 trihelix
657418 grail3.0009029402 trihelix
659988 grail3.0022049001 trihelix
660195 grail3.0106016201 trihelix
666639 grail3.0005026001 trihelix
676458 grail3.0029010501 trihelix
773164 fgenesh4_pg.C_LG_XII000939 trihelix Lactamase_B RMMBL
776769 fgenesh4_pg.C_LG_XVI000011 trihelix
778837 fgenesh4_pg.C_LG_XVIII000205 trihelix
801329 fgenesh4_pm.C_LG_V000421 trihelix
808708 fgenesh4_pm.C_LG_XVI000436 trihelix
810482 fgenesh4_pm.C_scaffold_70000033 trihelix
813372 fgenesh4_pm.C_scaffold_29000148 trihelix Myb_DNA-binding
816219 estExt_fgenesh4_pg.C_LG_II0629 trihelix
833447 estExt_fgenesh4_pm.C_LG_X0184 trihelix
835874 estExt_fgenesh4_pm.C_LG_XVIII0226 trihelix

General references

Nagano, Y. 2000. Several features of the GT-factor trihelix domain resemble those of the Myb DNA-binding domain. Plant Physiol. 124(2):491-4 PUBMEDID:11027698
Nagano, Y; Inaba, T; Furuhashi, H; Sasaki, Y. 2001. Trihelix DNA-binding protein with specificities for two distinct cis-elements: both important for light down-regulated and dark-inducible gene expression in higher plants. J. Biol. Chem. 276(25):22238-43 PUBMEDID:11301338
Smalle, J; Kurepa, J; Haegman, M; Gielen, J; Van Montagu, M; Van Der Straeten, D. 1998. The trihelix DNA-binding motif in higher plants is not restricted to the transcription factors GT-1 and GT-2. Proc. Natl. Acad. Sci. U.S.A. 95(6):3318-22 PUBMEDID:9501260
Zhou, DX. 1999. Regulatory mechanism of plant gene transcription by GT-elements and GT-factors. Trends Plant Sci 4(6):210-214 PUBMEDID:10366876