Plant Transcription factor database - Universität Potsdam
version: 3.0

Selaginella moellendorffii bHLH Family


Buck & Atchley. 2003: The basic helix-loop-helix (bHLH) family of proteins is a group of functionally diverse transcription factors found in both plants and animals. These proteins evolved early in eukaryotic cells before the split of animals and plants, but appear to function in lsquoplant-specificrsquo or lsquoanimal-specificrsquo processes. In animals bHLH proteins are involved in regulation of a wide variety of essential developmental processes. On the contrary, bHLH proteins have not been extensively studied in plants. Those that have been characterized function in anthocyanin biosynthesis, phytochrome signaling, globulin expression, fruit dehiscence, carpel and epidermal development.

Members of this family
  SHOULD possess HLH domain

Domain alignments

Benchmark against A. thaliana

The Sensitivity and Positive Predictive Value (PPV) were assessed for this family. The data reported by Bailey et al. 2003 for A. thaliana were taken as gold standard.

The gold standard reported 154 members for this family, 122 of which are present in ArabTFDB, giving a PPV of 0.92. Thirty-two additional members not present in ArabTFDB might be false negatives, giving a Sensitivity of 0.80.

This family is also present in:


There are 46 gene models in this family

Gene modelDescriptionDomains
114141 e_gw1.47.312.1 HLH
118904 e_gw1.59.232.1 HLH
16039 gw1.22.130.1 HLH
165311 estExt_Genewise1Plus.C_20067 HLH
165556 estExt_Genewise1Plus.C_20775 HLH
24892 gw1.6.345.1 HLH
34848 gw1.20.424.1 HLH
39143 gw1.38.291.1 HLH
402301 fgenesh2_pg.C_scaffold_0000306 HLH
402536 fgenesh2_pg.C_scaffold_0000541 HLH
402928 fgenesh2_pg.C_scaffold_0000933 HLH
403406 fgenesh2_pg.C_scaffold_1000243 HLH
404767 fgenesh2_pg.C_scaffold_2000755 HLH
405220 fgenesh2_pg.C_scaffold_3000443 HLH
405883 fgenesh2_pg.C_scaffold_4000457 HLH
407706 fgenesh2_pg.C_scaffold_7000337 HLH
409950 fgenesh2_pg.C_scaffold_11000333 HLH
409967 fgenesh2_pg.C_scaffold_11000350 HLH
411158 fgenesh2_pg.C_scaffold_14000211 HLH
411161 fgenesh2_pg.C_scaffold_14000214 HLH
412681 fgenesh2_pg.C_scaffold_18000257 HLH
413232 fgenesh2_pg.C_scaffold_20000093 HLH
413316 fgenesh2_pg.C_scaffold_20000177 HLH
418491 fgenesh2_pg.C_scaffold_38000089 HLH
419388 fgenesh2_pg.C_scaffold_42000088 HLH
421249 fgenesh2_pg.C_scaffold_50000138 HLH
422169 fgenesh2_pg.C_scaffold_55000079 HLH
424152 fgenesh2_pg.C_scaffold_65000101 HLH
424604 fgenesh2_pg.C_scaffold_68000085 ACT HLH
425336 fgenesh2_pg.C_scaffold_73000106 HLH
430716 fgenesh2_pg.C_scaffold_136000057 HLH
439190 estExt_fgenesh2_pg.C_50545 HLH TPP_enzyme_N
440893 estExt_fgenesh2_pg.C_130081 HLH
443113 estExt_fgenesh2_pg.C_300009 HLH
444782 estExt_fgenesh2_pg.C_470207 HLH
445783 estExt_fgenesh2_pg.C_610047 HLH
56610 gw1.38.467.1 HLH
72702 gw1.7.1432.1 HLH
73360 e_gw1.0.2357.1 HLH
75047 e_gw1.0.1441.1 HLH
77288 e_gw1.1.965.1 HLH
81013 e_gw1.4.1634.1 HLH
91237 e_gw1.12.485.1 HLH
91359 e_gw1.12.879.1 HLH
93546 e_gw1.14.526.1 HLH
94010 e_gw1.15.328.1 HLH

General references

Buck, MJ; Atchley, WR. 2003. Phylogenetic analysis of plant basic helix-loop-helix proteins. J. Mol. Evol. 56(6):742-50 PUBMEDID:12911037
Heim, MA; Jakoby, M; Werber, M; Martin, C; Weisshaar, B; Bailey, PC. 2003. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Mol. Biol. Evol. 20(5):735-47 PUBMEDID:12679534
Littlewood, TD; Evan, GI. 1995. Transcription factors 2: helix-loop-helix. Protein Profile 2(6):621-702 PUBMEDID:7553065
Massari, ME; Murre, C. 2000. Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms. Mol. Cell. Biol. 20(2):429-40 PUBMEDID:10611221
Quattrocchio, F; Wing, JF; van der Woude, K; Mol, JN; Koes, R. 1998. Analysis of bHLH and MYB domain proteins: species-specific regulatory differences are caused by divergent evolution of target anthocyanin genes. Plant J. 13(4):475-88 PUBMEDID:9680994