Plant Transcription factor database - Universität Potsdam
version: 3.0

Arabidopsis lyrata mTERF Family


Roberti et al. 2009: The MTERF family is a wide protein family, identified in Metazoa and plants, which consists of 4 subfamilies named MTERF1-4. Proteins belonging to this family are localized in mitochondria and have a modular architecture based on repetitions of a 30 amino acid module, the mTERF motif, containing leucine zipper-like heptads. The MTERF family includes the characterized transcription termination factors human mTERF, sea urchin mtDBP and Drosophila DmTTF. In vitro and in vivo studies show that these factors play different roles which are not restricted to transcription termination, but concern also transcription inititiation and the control of mtDNA replication. The multiplicity of functions could be related to the differences in the gene organization of the mitochondrial genomes. Studies on the function of human and Drosophila MTERF3 factor showed that the protein acts as negative regulator of mitochondrial transcription, possibly in cooperation with other still unknown factors. The complete elucidation of the role of the MTERF family members will allow to unravel the molecular mechanisms of mtDNA transcription and replication.

Members of this family
  SHOULD possess mTERF domain

Domain alignments

This family is also present in:


There are 42 gene models in this family

Gene modelDescriptionDomains
313019 fgenesh1_pm.C_scaffold_1001799 GTP_EFTU mTERF
315177 fgenesh1_pm.C_scaffold_2000210 mTERF
315190 fgenesh1_pm.C_scaffold_2000223 mTERF
338172 fgenesh1_pg.C_scaffold_2000271 mTERF
475136 fgenesh2_kg.2__266__AT1G61990.1 mTERF
475137 fgenesh2_kg.2__267__AT1G61980.1 mTERF
476555 fgenesh2_kg.2__1685__AT1G74120.1 mTERF
477061 fgenesh2_kg.2__2191__AT1G78930.1 mTERF
477089 fgenesh2_kg.2__2219__AT1G79220.1 mTERF
481036 fgenesh2_kg.4__96__AT2G21710.1 mTERF
482425 fgenesh2_kg.4__1485__AT2G34620.1 mTERF
482571 fgenesh2_kg.4__1631__AT2G36000.1 mTERF
484214 fgenesh2_kg.5__206__AT2G03050.1 mTERF
485072 fgenesh2_kg.5__1064__AT3G46950.1 mTERF
487623 fgenesh2_kg.6__757__AT5G07900.1 mTERF
489254 fgenesh2_kg.6__2388__AT5G23930.1 mTERF
490263 fgenesh2_kg.6__3397__AT4G02990.1 mTERF
490575 fgenesh2_kg.7__8__AT4G38160.2 mTERF
495499 fgenesh2_kg.8__1315__AT5G54180.1 mTERF
495645 fgenesh2_kg.8__1461__AT5G55580.1 mTERF
497370 fgenesh2_kg.270__3__AT2G34620.1 mTERF
497554 fgenesh2_kg.970__2__AT2G36000.1 mTERF
861095 Al_scaffold_0006_604 mTERF
893233 scaffold_200307.1 mTERF
893270 scaffold_200344.1 mTERF
893275 scaffold_200349.1 mTERF
893280 scaffold_200354.1 mTERF
893283 scaffold_200357.1 mTERF
893289 scaffold_200363.1 mTERF
893298 scaffold_200372.1 mTERF
893300 scaffold_200374.1 mTERF
894067 scaffold_201141.1 mTERF
898263 scaffold_302233.1 mTERF
903808 scaffold_403309.1 mTERF
907562 scaffold_503266.1 mTERF
907730 scaffold_503434.1 Pro_isomerase mTERF
907868 scaffold_503572.1 mTERF
914700 scaffold_702442.1 mTERF
915404 scaffold_703146.1 mTERF
917019 scaffold_800419.1 mTERF
917622 scaffold_801022.1 mTERF
919822 scaffold_803222.1 mTERF

General references

Roberti, M; Polosa, PL; Bruni, F; Manzari, C; Deceglie, S; Gadaleta, MN; Cantatore, P. 2009. The MTERF family proteins: Mitochondrial transcription regulators and beyond. Biochim. Biophys. Acta PUBMEDID:19366610