Plant Transcription factor database - Universität Potsdam
version: 3.0

Arabidopsis thaliana mTERF Family

Description

Roberti et al. 2009: The MTERF family is a wide protein family, identified in Metazoa and plants, which consists of 4 subfamilies named MTERF1-4. Proteins belonging to this family are localized in mitochondria and have a modular architecture based on repetitions of a 30 amino acid module, the mTERF motif, containing leucine zipper-like heptads. The MTERF family includes the characterized transcription termination factors human mTERF, sea urchin mtDBP and Drosophila DmTTF. In vitro and in vivo studies show that these factors play different roles which are not restricted to transcription termination, but concern also transcription inititiation and the control of mtDNA replication. The multiplicity of functions could be related to the differences in the gene organization of the mitochondrial genomes. Studies on the function of human and Drosophila MTERF3 factor showed that the protein acts as negative regulator of mitochondrial transcription, possibly in cooperation with other still unknown factors. The complete elucidation of the role of the MTERF family members will allow to unravel the molecular mechanisms of mtDNA transcription and replication.

Members of this family
  SHOULD possess mTERF domain

Domain alignments

This family is also present in:

References

There are 36 gene models in this family



Gene modelDescriptionDomains
AT1G21150.1 mitochondrial transcription termination factor family protein / mTERF family protein mTERF
AT1G56380.1 mitochondrial transcription termination factor family protein / mTERF family protein mTERF
AT1G61960.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT1G61970.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT1G61980.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT1G61990.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT1G62010.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT1G62085.1 mitochondrial transcription termination factor family protein / mTERF family protein mTERF
AT1G62110.1 mitochondrial transcription termination factor family protein / mTERF family protein mTERF
AT1G62120.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT1G62150.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT1G62490.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT1G74120.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT1G78930.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT1G79220.1 mitochondrial transcription termination factor family protein / mTERF family protein mTERF
AT2G03050.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT2G21710.1 EMB2219 (EMBRYO DEFECTIVE 2219) mTERF
AT2G34620.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT2G36000.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT2G36000.2 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT2G44020.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT3G18870.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT3G46950.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT3G60400.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT4G02990.1 mitochondrial transcription termination factor family protein / mTERF family protein mTERF
AT4G14605.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT4G19650.1 similar to mitochondrial transcription termination factor-related / mTERF-related [Arabidopsis thaliana] (TAIR:AT5G45113.1); similar to unnamed protein product [Vitis vinifera] (GB:CAO44451.1); contains InterPro domain Mitochodrial transcription terminat mTERF
AT4G38160.1 PDE191 (PIGMENT DEFECTIVE 191) mTERF
AT4G38160.2 PDE191 (PIGMENT DEFECTIVE 191) mTERF
AT5G06810.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT5G07900.1 mitochondrial transcription termination factor family protein / mTERF family protein mTERF
AT5G23930.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT5G45113.1 mitochondrial transcription termination factor-related / mTERF-related mTERF
AT5G54180.1 PTAC15 (PLASTID TRANSCRIPTIONALLY ACTIVE15) mTERF
AT5G55580.1 mitochondrial transcription termination factor family protein / mTERF family protein mTERF
AT5G64950.1 mitochondrial transcription termination factor-related / mTERF-related mTERF

General references

Roberti, M; Polosa, PL; Bruni, F; Manzari, C; Deceglie, S; Gadaleta, MN; Cantatore, P. 2009. The MTERF family proteins: Mitochondrial transcription regulators and beyond. Biochim. Biophys. Acta PUBMEDID:19366610