Plant Transcription factor database - Universität Potsdam
version: 3.0

Oryza sativa subsp. indica mTERF Family


Roberti et al. 2009: The MTERF family is a wide protein family, identified in Metazoa and plants, which consists of 4 subfamilies named MTERF1-4. Proteins belonging to this family are localized in mitochondria and have a modular architecture based on repetitions of a 30 amino acid module, the mTERF motif, containing leucine zipper-like heptads. The MTERF family includes the characterized transcription termination factors human mTERF, sea urchin mtDBP and Drosophila DmTTF. In vitro and in vivo studies show that these factors play different roles which are not restricted to transcription termination, but concern also transcription inititiation and the control of mtDNA replication. The multiplicity of functions could be related to the differences in the gene organization of the mitochondrial genomes. Studies on the function of human and Drosophila MTERF3 factor showed that the protein acts as negative regulator of mitochondrial transcription, possibly in cooperation with other still unknown factors. The complete elucidation of the role of the MTERF family members will allow to unravel the molecular mechanisms of mtDNA transcription and replication.

Members of this family
  SHOULD possess mTERF domain

Domain alignments

This family is also present in:


There are 29 gene models in this family

Gene modelDescriptionDomains
OsIBCD007123 Chr02_3880,1737,,,1,1737, mTERF
OsIBCD007982 Chr02_5136,2472,,,1,2472, mTERF
OsIBCD008183 Chr02_5424,1377,,,1,1377, mTERF
OsIBCD017999 Chr05_3187,1359,,,1,1359, mTERF
OsIBCD019884 Chr06_1178,924,,,1,924, mTERF
OsIBCD019885 Chr06_1179,2304,,,1,2304, mTERF
OsIBCD019886 Chr06_1183,1440,,,1,1440, mTERF
OsIBCD019888 Chr06_1188,2031,,,1,2031, LRRNT_2 mTERF
OsIBCD022277 Chr07_293,1827,,,1,1827, mTERF
OsIBCD024018 Chr07_3282,1512,,,1,1512, mTERF
OsIBCD027179 Chr08_4217,1014,,,1,1014, mTERF
OsIBCD029383 Chr09_3230,1623,,,1,1623, mTERF
OsIBCD032129 Chr11_838,1146,,,1,1146, mTERF
OsIBCD032304 Chr11_1120,1254,,,1,1254, mTERF
OsIBCD037942 Chr02_3666,840,,,1,840, mTERF
OsIBCD038851 Chr03_2368,906,,,1,906, mTERF
OsIBCD039496 Chr03_5657,930,,,1,930, mTERF
OsIBCD040525 Chr04_4801,1182,,,1,1182, mTERF
OsIBCD041190 Chr05_3123,1200,,,1,1200, mTERF
OsIBCD041191 Chr05_3128,1098,,,1,1098, mTERF
OsIBCD041816 Chr06_1177,1179,,,1,1179, mTERF
OsIBCD041817 Chr06_1180,1182,,,1,1182, mTERF
OsIBCD041819 Chr06_1184,1182,,,1,1182, mTERF
OsIBCD041821 Chr06_1186,1137,,,1,1137, mTERF
OsIBCD041822 Chr06_1189,1182,,,1,1182, mTERF
OsIBCD042902 Chr07_1822,1728,,,1,1728, mTERF
OsIBCD044130 Chr08_4059,1002,,,1,1002, mTERF
OsIBCD045818 Chr11_839,1377,,,1,1377, mTERF
OsIBCD045820 Chr11_843,1179,,,1,1179, mTERF

General references

Roberti, M; Polosa, PL; Bruni, F; Manzari, C; Deceglie, S; Gadaleta, MN; Cantatore, P. 2009. The MTERF family proteins: Mitochondrial transcription regulators and beyond. Biochim. Biophys. Acta PUBMEDID:19366610