Plant Transcription factor database - Universität Potsdam
version: 3.0

Zea mays mTERF Family


Roberti et al. 2009: The MTERF family is a wide protein family, identified in Metazoa and plants, which consists of 4 subfamilies named MTERF1-4. Proteins belonging to this family are localized in mitochondria and have a modular architecture based on repetitions of a 30 amino acid module, the mTERF motif, containing leucine zipper-like heptads. The MTERF family includes the characterized transcription termination factors human mTERF, sea urchin mtDBP and Drosophila DmTTF. In vitro and in vivo studies show that these factors play different roles which are not restricted to transcription termination, but concern also transcription inititiation and the control of mtDNA replication. The multiplicity of functions could be related to the differences in the gene organization of the mitochondrial genomes. Studies on the function of human and Drosophila MTERF3 factor showed that the protein acts as negative regulator of mitochondrial transcription, possibly in cooperation with other still unknown factors. The complete elucidation of the role of the MTERF family members will allow to unravel the molecular mechanisms of mtDNA transcription and replication.

Members of this family
  SHOULD possess mTERF domain

Domain alignments

This family is also present in:


There are 39 gene models in this family

Gene modelDescriptionDomains
GRMZM2G000610_P01 mTERF
GRMZM2G000610_P02 mTERF
GRMZM2G012204_P01 mTERF
GRMZM2G012999_P01 mTERF
GRMZM2G017355_P01 mTERF
GRMZM2G017429_P01 mTERF
GRMZM2G023257_P01 mTERF
GRMZM2G024386_P01 mTERF
GRMZM2G024550_P01 mTERF
GRMZM2G027142_P01 mTERF
GRMZM2G029933_P01 mTERF
GRMZM2G029933_P03 mTERF
GRMZM2G034217_P01 mTERF
GRMZM2G034217_P02 mTERF
GRMZM2G060114_P01 mTERF
GRMZM2G060114_P02 mTERF
GRMZM2G061542_P01 mTERF
GRMZM2G062910_P01 mTERF
GRMZM2G065548_P01 mTERF
GRMZM2G065572_P01 mTERF
GRMZM2G067084_P03 mTERF
GRMZM2G093822_P01 mTERF
GRMZM2G093822_P02 mTERF
GRMZM2G113181_P01 mTERF
GRMZM2G113181_P02 mTERF
GRMZM2G119921_P01 mTERF
GRMZM2G119921_P02 mTERF
GRMZM2G126694_P01 mTERF
GRMZM2G130773_P01 mTERF
GRMZM2G130773_P02 mTERF
GRMZM2G132709_P01 mTERF
GRMZM2G132709_P02 mTERF
GRMZM2G142150_P01 mTERF
GRMZM2G157716_P01 mTERF
GRMZM2G159766_P01 mTERF
GRMZM2G161146_P01 mTERF
GRMZM2G164120_P01 mTERF
GRMZM2G168665_P01 mTERF
GRMZM2G177019_P01 mTERF

General references

Roberti, M; Polosa, PL; Bruni, F; Manzari, C; Deceglie, S; Gadaleta, MN; Cantatore, P. 2009. The MTERF family proteins: Mitochondrial transcription regulators and beyond. Biochim. Biophys. Acta PUBMEDID:19366610